Renal assessment workspaceCrCl + eGFR
yr
mg/L
Special populations
Lee-Dang Method (Lee & Dang, Spinal Cord 2011)
CLM = C-G with SCr floored at 1.0 mg/dL.
CLSCI = 2.3 × CLM0.7
Underestimates actual drug clearance by <5% vs 71–141% overestimation with standard equations. Validated for vancomycin and aminoglycosides.
CLM = C-G with SCr floored at 1.0 mg/dL.
CLSCI = 2.3 × CLM0.7
Underestimates actual drug clearance by <5% vs 71–141% overestimation with standard equations. Validated for vancomycin and aminoglycosides.
Limb Mass Percentages
Segment weights expressed as % of total body mass. Post-amputation weight is scaled up to estimate pre-amputation TBW for Cockcroft-Gault.
References: Osterkamp LK. J Am Diet Assoc. 1995;95(2):215–218 | Dempster WT, Gaughran GRL. Am J Anat. 1967;120(1):33–54.
Segment weights expressed as % of total body mass. Post-amputation weight is scaled up to estimate pre-amputation TBW for Cockcroft-Gault.
References: Osterkamp LK. J Am Diet Assoc. 1995;95(2):215–218 | Dempster WT, Gaughran GRL. Am J Anat. 1967;120(1):33–54.
Select amputated segments:
Enter patient values — serum creatinine and/or cystatin C — then Calculate for CrCl and eGFR.
For use by licensed clinicians. Interpret estimates in the patient’s clinical context, especially when kidney function is changing.
NIH / NLM — FDA Drug Labeling
Drug dosing is not generated on this page. Search the current U.S. prescribing information, then use the renal estimate and method specified by that source.
TheraCALC — Renal Function Assessment | Powered by the TheraIQ engine | theracalc.com
Renal estimates are calculated locally using the methods shown on this page. TheraCALC does not rely on any third-party clinical decision-support service.
For use by licensed clinicians only. Renal estimates require clinical judgment and may be unreliable when kidney function is not at steady state.
Renal estimates are calculated locally using the methods shown on this page. TheraCALC does not rely on any third-party clinical decision-support service.
For use by licensed clinicians only. Renal estimates require clinical judgment and may be unreliable when kidney function is not at steady state.
v2.3.48 · 2026-08-13