Renal assessment workspaceCrCl + eGFR
yr
mg/L
Special populations
SCI interpretation boundary
Use SCI as an uncertainty flag, not a one-number answer. Reduced muscle mass, immobility, injury level, and time since injury can make creatinine-based estimates look falsely high.
Lee-Dang special estimate: CLM = C-G with SCr floored at 1.0 mg/dL; CLSCI = 2.3 × CLM0.7. Best-supported for chronic SCI vancomycin/aminoglycoside dosing; for other drugs, reconcile with labeling, cystatin C, measured clearance, and monitoring.
Use SCI as an uncertainty flag, not a one-number answer. Reduced muscle mass, immobility, injury level, and time since injury can make creatinine-based estimates look falsely high.
Lee-Dang special estimate: CLM = C-G with SCr floored at 1.0 mg/dL; CLSCI = 2.3 × CLM0.7. Best-supported for chronic SCI vancomycin/aminoglycoside dosing; for other drugs, reconcile with labeling, cystatin C, measured clearance, and monitoring.
Limb Mass Percentages
Segment weights expressed as % of total body mass. Post-amputation weight is scaled up to estimate pre-amputation TBW for Cockcroft-Gault.
References: Osterkamp LK. J Am Diet Assoc. 1995;95(2):215–218 | Dempster WT, Gaughran GRL. Am J Anat. 1967;120(1):33–54.
Segment weights expressed as % of total body mass. Post-amputation weight is scaled up to estimate pre-amputation TBW for Cockcroft-Gault.
References: Osterkamp LK. J Am Diet Assoc. 1995;95(2):215–218 | Dempster WT, Gaughran GRL. Am J Anat. 1967;120(1):33–54.
Select one level for each affected limb
No amputation levels selected
Missing limb mass0.0%
Post-amputationNot entered
Pre-amputation estimate—
Additional clinical factors
Use when patient factors may make creatinine or cystatin C less representative of true filtration. These do not change the equations; they change how strongly the estimates are interpreted.
Enter patient values — serum creatinine and/or cystatin C — then Calculate for CrCl and eGFR.
For use by licensed clinicians. Interpret estimates in the patient’s clinical context, especially when kidney function is changing.
NIH / NLM — FDA Drug Labeling
Drug dosing is not generated on this page. Search the current U.S. prescribing information, then use the renal estimate and method specified by that source.
v2.3.63 · 2026-10-11